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Biology and Medicine

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An Introduction

Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology.

Exploring the Controversy

An estimated 100 million nonhuman vertebrates worldwide--including primates, dogs, cats, rabbits, hamsters, birds, rats, and mice--are bred, captured, or otherwise acquired every year for research purposes. Much of this research is seriously detrimental to the welfare of these animals, causing pain, distress, injury, or death. This book explores the ethical controversies that have arisen over animal research, examining closely the complex scientific, philosophical, moral, and legal issues involved.

Using the tools of information technology to understand the molecular machinery of the cell offers both challenges and opportunities to computational scientists. Over the past decade, novel algorithms have been developed both for analyzing biological data and for synthetic biology problems such as protein engineering.

The Computational Approach to Biological Vision

Seeing has puzzled scientists and philosophers for centuries and continues to do so. This new edition of a classic text offers an accessible but rigorous introduction to the computational approach to understanding biological visual systems.

An Introduction to Molecular Biology

Recent research in molecular biology has produced a remarkably detailed understanding of how living things operate. Becoming conversant with the intricacies of molecular biology and its extensive technical vocabulary can be a challenge, though, as introductory materials often seem more like a barrier than an invitation to the study of life.

A Survey of Practical Models, Algorithms, and Numerical Methods

There are many excellent computational biology resources now available for learning about methods that have been developed to address specific biological systems, but comparatively little attention has been paid to training aspiring computational biologists to handle new and unanticipated problems. This text is intended to fill that gap by teaching students how to reason about developing formal mathematical models of biological systems that are amenable to computational analysis.

Edited by Elliott Sober

These essays by leading scientists and philosophers address conceptual issues that arise in the theory and practice of evolutionary biology. The third edition of this widely used anthology has been substantially revised and updated. Four new sections have been added: on women in the evolutionary process, evolutionary psychology, laws in evolutionary theory, and race as social construction or biological reality. Other sections treat fitness, units of selection, adaptationism, reductionism, essentialism, species, phylogenetic inference, cultural evolution, and evolutionary ethics.

This introductory text offers a clear exposition of the algorithmic principles driving advances in bioinformatics. Accessible to students in both biology and computer science, it strikes a unique balance between rigorous mathematics and practical techniques, emphasizing the ideas underlying algorithms rather than offering a collection of apparently unrelated problems.

This textbook for instruction in biomedical research ethics can also serve as a valuable reference for professionals in the field of bioethics. The 149 cases included in the book are grouped in nine chapters, each of which covers a key area of debate in the field. Some of the case studies are classics, including the famous cases of the Tuskegee Syphilis Study (in which subjects with syphilis were not given treatment) and the Willowbrook hepatitis studies (in which institutionalized subjects were intentionally exposed to hepatitis).

Medicine and Morality in a Time of Crisis

The war on terrorism and the threat of chemical and biological weapons have brought a new urgency to already complex moral and bioethical questions. In the Wake of Terror presents thought-provoking essays on many of the troubling issues facing American society, written by experts from the fields of medicine, health care policy, law, political science, history, philosophy, and theology.

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