Federal regulations that govern research misconduct in biomedicine have not been able to prevent an ongoing series of high-profile cases of fabricating, falsifying, or plagiarizing scientific research. In this book, Barbara Redman looks critically at current research misconduct policy and proposes a new approach that emphasizes institutional context and improved oversight.
On September 2, 1971, the chemist Paul Lauterbur had an idea that would change the practice of medical research. Considering recent research findings about the use of nuclear magnetic resonance (NMR) signals to detect tumors in tissue samples, Lauterbur realized that the information from NMR signals could be recovered in the form of images—and thus obtained noninvasively from a living subject. It was an unexpected epiphany: he was eating a hamburger at the time. Lauterbur rushed out to buy a notebook in which to work out his idea; he completed his notes a few days later.
Many books explain what is known about the universe. This book investigates what cannot be known. Rather than exploring the amazing facts that science, mathematics, and reason have revealed to us, this work studies what science, mathematics, and reason tell us cannot be revealed. In The Outer Limits of Reason, Noson Yanofsky considers what cannot be predicted, described, or known, and what will never be understood. He discusses the limitations of computers, physics, logic, and our own thought processes.
The extraordinary and adorable antics of penguins attract thousands of tourists every year to remote and icy locations. Penguins never fail to make people smile; wild penguins waddle up and inspect us as if we were just another kind of flightless creature walking on two legs. In this book, the vibrant world of penguins is shown in all its glory by David Tipling, who has trekked to beautiful and faraway locations to capture these birds in their natural habitats.
Synthetic biology, which aims to design and build organisms that serve human needs, has potential applications that range from producing biofuels to programming human behavior. The emergence of this new form of biotechnology, however, raises a variety of ethical questions—first and foremost, whether synthetic biology is intrinsically troubling in moral terms. Is it an egregious example of scientists “playing God”?
With robots, we are inventing a new species that is part material and part digital. The ambition of modern robotics goes beyond copying humans, beyond the effort to make walking, talking androids that are indistinguishable from people. Future robots will have superhuman abilities in both the physical and digital realms. They will be embedded in our physical spaces, with the ability to go where we cannot, and will have minds of their own, thanks to artificial intelligence. They will be fully connected to the digital world, far better at carrying out online tasks than we are.
The biosphere—the Earth’s thin layer of life—dates from nearly four billion years ago, when the first simple organisms appeared. Many species have exerted enormous influence on the biosphere’s character and productivity, but none has transformed the Earth in so many ways and on such a scale as Homo sapiens. In Harvesting the Biosphere, Vaclav Smil offers an interdisciplinary and quantitative account of human claims on the biosphere’s stores of living matter, from prehistory to the present day.
Sitting on the beach on a sunny summer day, we enjoy the steady advance and retreat of the waves. In the water, enthusiastic waders jump and shriek with pleasure when a wave hits them. But where do these waves come from? How are they formed and why do they break on the shore? In Waves, Fredric Raichlen traces the evolution of waves, from their generation in the deep ocean to their effects on the coast.
If you touch something hot, it hurts. You snatch your hand away from the hot thing immediately. Obviously. But what is really happening, biologically‚ÄĒand emotionally? In Understanding Pain, Fernando Cervero explores the mechanisms and the meaning of pain. You touch something hot and your brain triggers a reflex action that causes you to withdraw your hand, protecting you from injury. That kind of pain, Cervero explains, is actually good for us; it acts as an alarm that warns us of danger and keeps us away from harm.
Geologists in the field climb hills and hang onto craggy outcrops; they put their fingers in sand and scratch, smell, and even taste rocks. Beginning in 2004, however, a team of geologists and other planetary scientists did field science in a dark room in Pasadena, exploring Mars from NASA’s Jet Propulsion Laboratory (JPL) by means of the remotely operated Mars Exploration Rovers (MER).