Crucial to understanding how the brain works is connectivity, and the centerpiece of brain connectivity is the connectome, a comprehensive description of how neurons and brain regions are connected. The human brain is a network of extraordinary complexity--a network not by way of metaphor, but in a precise and mathematical sense: an intricate web of billions of neurons connected by trillions of synapses. How this network is connected is important for virtually all facets of the brain’s integrative function.
"The book is exceptionally to the point—and useful. I’ve recommended it to our senior staff for themselves and for the faculty they deal with. Despite the title limiting it to “Biomedical”, I found it more widely applicable. The examples are all “biomedical”, but the rest is not limited."
-Lita Nelsen, Director, Technology Licensing Office, Massachusetts Institute of Technology
If you touch something hot, it hurts. You snatch your hand away from the hot thing immediately. Obviously. But what is really happening, biologically–and emotionally? In Understanding Pain, Fernando Cervero explores the mechanisms and the meaning of pain. You touch something hot and your brain triggers a reflex action that causes you to withdraw your hand, protecting you from injury. That kind of pain, Cervero explains, is actually good for us; it acts as an alarm that warns us of danger and keeps us away from harm.
The introduction of high-throughput methods has transformed biology into a data-rich science. Knowledge about biological entities and processes has traditionally been acquired by thousands of scientists through decades of experimentation and analysis. The current abundance of biomedical data is accompanied by the creation and quick dissemination of new information. Much of this information and knowledge, however, is represented only in text form--in the biomedical literature, lab notebooks, Web pages, and other sources.
By adulthood, most of us have become experts in human behavior, able to make sense of the myriad behaviors we find in environments ranging from the family home to the local mall and beyond. In philosophy of mind, our understanding of others has been largely explained in terms of knowing others’ beliefs and desires; describing others’ behavior in these terms is the core of what is known as folk psychology.
Genetic engineering has a wide range of cultural, economic, and ethical implications, yet it has become almost an article of faith that regulatory decisions about biotechnology be based only on evidence of specific quantifiable risks; to consider anything else is said to “politicize” regulation. In this study of social protest against genetically engineered food, Abby Kinchy turns the conventional argument on its head.
An estimated 100 million nonhuman vertebrates worldwide--including primates, dogs, cats, rabbits, hamsters, birds, rats, and mice--are bred, captured, or otherwise acquired every year for research purposes. Much of this research is seriously detrimental to the welfare of these animals, causing pain, distress, injury, or death. This book explores the ethical controversies that have arisen over animal research, examining closely the complex scientific, philosophical, moral, and legal issues involved.
Birdsong may seem to us to be the purest expression of joy, but in fact when a male bird bursts into melodious song, he is warning off other males and advertising his availability to females. He may also engage in spectacular displays of plumage, dance-like movements, or even acrobatics (tree-based or aerial)--all as part of courtship. The female, meanwhile, assesses his vocalization, plumage, and territory before accepting him as a mate.
Linguists have mapped the topography of language behavior in many languages in intricate detail. To understand how the brain supports language function, however, we must take into account the principles and regularities of neural function. Mechanisms of neurolinguistic function cannot be inferred solely from observations of normal and impaired language. In The Neural Architecture of Grammar, Stephen Nadeau develops a neurologically plausible theory of grammatic function.
Over the last three million years or so, our lineage has diverged sharply from those of our great ape relatives. Change has been rapid (in evolutionary terms) and pervasive. Morphology, life history, social life, sexual behavior, and foraging patterns have all shifted sharply away from other great apes. No other great ape lineage--including those of chimpanzees and gorillas--seems to have undergone such a profound transformation.
Why our dependence on coal-produced energy is bad for our health: a physician maps the connections of burning coal to death and disease.
An argument against the “lifeboat ethic” of contemporary bioethics that views medicine as a commodity rather than a tradition of care and caring.
Lynn MargulisCeleste A. AsikainenScientists elucidate the astounding collective sensory capacity of Earth and its evolution through time.
Two leading physicians’ prescription for solving our health care problems: organizing the fragmented system that delivers care.
Jeremy R. GarrettA balanced, accessible discussion of whether and on what grounds animal research can be ethically justified.
Lynn MargulisCeleste A. Asikainen
Jeremy R. Garrett
