Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment.
Although there is scientific consensus that genetic factors play a substantial role in an individual’s vulnerability to drug or alcohol addiction, specific genetic variables linked to risk or resilience remain elusive. Understanding how genetic factors contribute to addiction may require focusing on intermediary mechanisms, or intermediate phenotypes, that connect genetic variation and risk for addiction. This book offers a comprehensive review of this mechanistic-centered approach and the most promising intermediate phenotypes identified in empirical research.
This book proposes a transdisciplinary approach to investigating human motor control that synthesizes musculoskeletal biomechanics and neural control. The authors argue that this integrated approach—which uses the framework of robotics to understand sensorimotor control problems—offers a more complete and accurate description than either a purely neural computational approach or a purely biomechanical one.
Reflection on the nature of hallucination has relevance for many traditional philosophical debates concerning the nature of the mind, perception, and our knowledge of the world. In recent years, neuroimaging techniques and scientific findings on the nature of hallucination, combined with interest in new philosophical theories of perception such as disjunctivism, have brought the topic of hallucination once more to the forefront of philosophical thinking.
In Feeling Beauty, G. Gabrielle Starr argues that understanding the neural underpinnings of aesthetic experience can reshape our conceptions of aesthetics and the arts. Drawing on the tools of both cognitive neuroscience and traditional humanist inquiry, Starr shows that neuroaesthetics offers a new model for understanding the dynamic and changing features of aesthetic life, the relationships among the arts, and how individual differences in aesthetic judgment shape the varieties of aesthetic experience.
The issues of mental causation, consciousness, and free will have vexed philosophers since Plato. In this book, Peter Tse examines these unresolved issues from a neuroscientific perspective. In contrast with philosophers who use logic rather than data to argue whether mental causation or consciousness can exist given unproven first assumptions, Tse proposes that we instead listen to what neurons have to say. Because the brain must already embody a solution to the mind–body problem, why not focus on how the brain actually realizes mental causation?
Imagine the astonishment felt by neuroscientist Rodrigo Quian Quiroga when he found a fantastically precise interpretation of his research findings in a story written by the great Argentinian fabulist Jorge Luis Borges fifty years earlier. Quian Quiroga studies the workings of the brain--in particular how memory works--one of the most complex and elusive mysteries of science. He and his fellow neuroscientists have at their disposal sophisticated imaging equipment and access to information not available just twenty years ago.
The brain and the nervous system are our most cultural organs. Our nervous system is especially immature at birth, our brain disproportionately small in relation to its adult size and open to cultural sculpting at multiple levels. Recognizing this, the new field of neuroanthropology places the brain at the center of discussions about human nature and culture. Anthropology offers brain science more robust accounts of enculturation to explain observable difference in brain function; neuroscience offers anthropology evidence of neuroplasticity’s role in social and cultural dynamics.
If you touch something hot, it hurts. You snatch your hand away from the hot thing immediately. Obviously. But what is really happening, biologically–and emotionally? In Understanding Pain, Fernando Cervero explores the mechanisms and the meaning of pain. You touch something hot and your brain triggers a reflex action that causes you to withdraw your hand, protecting you from injury. That kind of pain, Cervero explains, is actually good for us; it acts as an alarm that warns us of danger and keeps us away from harm.
The study of consciousness has advanced rapidly over the last two decades. And yet there is no clear path to creating models for a direct science of human experience or for integrating its insights with those of neuroscience, psychology, and philosophy. In Inner Experience and Neuroscience, Donald Price and James Barrell show how a science of human experience can be developed through a strategy that integrates experiential paradigms with methods from the natural sciences.