Published: 8 February 2001
This manuscript reviews the current stance and the pertinent problems of transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (fMRI) as brain mapping methodologies. The missing structure-function relation limits the use of TMS, whereas the uncertainty about the functional significance of activated cortical regions might render interpretation of fMRI studies difficult. Advances in image processing, however, allowed for 3- dimensional real-time visual guidance of TMS and integration with fMRI data. We describe the method used to coregister TMS and fMRI and present examples where a multimodality neuroimaging approach might add to our understanding of normal and pathological brain function.
Keywords: functional magnetic resonance imaging (fMRI), transcranial magnetic stimulation (TMS), brain mapping
Multimodality
Neuroimaging: Research and Clinical Applications
by Timo Krings, MD, Marchus H.T. Reinges, MD, Henrik Foltys, MD, G. Rees
Cosgrove, MD, Armin Thron, MD