423 pp., 7 x 10 in,
- Published: June 15, 1994
- Publisher: The MIT Press
- Published: November 8, 1996
- Publisher: The MIT Press
Following the successful format of the first volume on long-term potentiation—a leading candidate for the neuronal basis of learning and memory—Volume 2 brings together the most recent data and hypotheses by top neuroscientists regarding the mechanisms of this phenomenon and of long-term depression (LTD).
Following the successful format of the first volume on long- term potentiation—a leading candidate for the neuronal basis of learning and memory—Volume 2 brings together the most recent data and hypotheses by top neuroscientists regarding the mechanisms of this phenomenon and of long-term depression (LTD). The book is divided into several sections covering different aspects of the field ranging from molecular mechanisms of plasticity to computational neurobiology. It revisits some of the major points covered in Volume 1, updating them in this fast-moving field. It also introduces several new issues that have arisen since then. Of the many possible new topics that could have been added, the editors have focused on retrograde messengers and the mechanisms and functions of LTP and LTD because they are the subject of much interest, research, and controversy. The section on retrograde messengers deals primarily with nitric oxide.
Bradford Books imprint
This up-to-date addition to the series on Long-Term Potentiation makes the series the definitive work in the field. The latest volume covers the entire spectrum of investigation on this crucial phenomenon, from molecules to models, and is certain to play a major role in setting the future direction of the field.
Bruce L. McNaughton, Director, ARL Division of Neural Systems, Memory and Aging; Professor, Psychology and Physiology, University of Arizona
This is the third in the series of compilations by Baudry and DAvis that provides an indispensible documentation of the discoveries and controversies about the phenomena of LTP. This volume brings us up to date on the molecular-genetic and subcellular substrates of synaptic potentiation and depression, and it explores new applications of what we have learned about LTP to understanding network information processing using computational models and analyses of the population dynamics of real biological systems.
Howard Eichenbaum, Professor of Psychology, Boston University
The publication of Volume 3 in the Long-Term Potentiation series so soon after volume 2 is testament to the continuing fascination neuroscientists have with processes of synaptic plasticity. As in earlier volumes, coverage ranges from mechanisms to molecular and cellular processes to networks and systems. I was delighted to see discussions of long-term depression (LTD) in hippocampus and increased coverage of processes of synaptic plasticity and LTD in the cerebellum. Another important feature of this volume is the increased emphasis on mathematical/computational models of synaptic plasticity in networks. This volume is a must for anyone interested in synaptic plasticity.
Richard F. Thompson, Keck Professor of Psychology and Biological Sciences; Director, Neurosciences Program, University of Southern California