Peter J. Uhlhaas

Peter J. Uhlhaas is Professor of Translational Neuroscience and Clinical Psychology at the University of Glasgow's Institute of Neuroscience and Psychology.

  • Youth Mental Health

    A Paradigm for Prevention and Early Intervention

    Peter J. Uhlhaas and Stephen J. Wood

    Experts discuss the potential of early intervention to transform outcomes for people with mental disorders.

    Mental illness represents one of the largest disease burdens worldwide, yet treatments have been largely ineffective in improving the quality of life for millions of affected individuals—in part because approaches taken have focused on late-stage disorders in adulthood. This volume shifts the focus by placing the developmental stage of “youth” at the center of mental health. The contributors challenge current nosology, explore mechanisms that underlie the emergence of mental disorders, and propose a framework to guide early intervention. Offering recommendations for the future, the book holds that early intervention in youth has the potential to transform outcomes for people with mental disorders and to reconfigure the landscape of mental health.

    The contributors discuss epidemiology, classification, and diagnostic issues, including the benefits of clinical staging; the context for emerging mental disorders, including both biological and sociocultural processes; biological mechanisms underlying risk for psychopathology, including aspects of neural circuitry; and developing and implementing prevention and early intervention, including assessment and intervention modalities and knowledge translation in early treatment of schizophrenia.

    Contributors

    Nicholas B. Allen, Mario Alvarez-Jimenez, G. Paul Amminger, Shelli Avenevoli, Hannah F. Behrendt, Tolulope Bella-Awusah,, Byron K. Y. Bitanihirwe, Drew A. Blasco, John Cahill, Joanne S. Carpenter, Andrew M. Chanen, Eric Y. H. Chen, Shane D. Colombo, Christoph U. Correll, Christopher G. Davey, Kim Q. Do, Damien A. Fair, Helen L. Fisher, Sophia Frangou, John Gleeson, Robert K. Heinssen, Ian B. Hickie, Frank Iorfino, Peter B. Jones, Matcheri S. Keshavan, Kerstin Konrad, Phuong Thao D. Le, Francis Lee, Leslie Leve, Sarah A. Lieff, Cindy H. Liu, Beatriz Luna, Patrick D. McGorry, Urvakhsh Meherwan Mehta, Andreas Meyer-Lindenberg, Shreya V. Nellur, Cristopher Niell, Merete Nordentoft, Dost Öngür, George C. Patton, Tomáš Paus, Ulrich Reininghaus, Bernalyn Ruiz, Fred Sabb, Akira Sawa, Michael Schoenbaum, Gunter Schumann, Elizabeth M. Scott, Jai Shah, Vinod H. Srihari, Ezra Susser, John Torous, Peter J. Uhlhaas, Swapna K. Verma, T. Wilson Woo, Stephen J. Wood, Lawrence Yang, Alison R. Yung

    • Hardcover $70.00 £58.00

Contributor

  • Schizophrenia

    Schizophrenia

    Evolution and Synthesis

    Steven M. Silverstein, Bita Moghaddam, and Til Wykes

    Leading researchers address conceptual and technical issues in schizophrenia and suggest novel strategies for advancing research and treatment.

    Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment.

    The contributors address a wide range of critical issues: the construct of schizophrenia itself; etiology, risk, prediction, and prevention; different methods of modeling the disorder; and treatment development and delivery. They identify crucial gaps in our knowledge and offer creative but feasible suggestions. These strategies include viewing schizophrenia as a heterogeneous group of conditions; adopting specific new approaches to prediction and early intervention; developing better integration of data across genetics, imaging, perception, cognition, phenomenology, and other fields; and moving toward an evidence-based, personalized approach to treatment requiring rational clinical decision-making to reduce functional disability.

    Contributors Robert Bittner, Robert W. Buchanan, Kristin S. Cadenhead, William T. Carpenter, Jr., Aiden Corvin, Daniel Durstewitz, André A. Fenton, Camilo de la Fuente-Sandoval, Jay A. Gingrich, Joshua A. Gordon, Chloe Gott, Peter B. Jones, René S. Kahn, Richard Keefe, Wolfgang Kelsch, James L. Kennedy, Matcheri S. Keshavan, Angus W. MacDonald III, Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Kevin J. Mitchell, Bita Moghaddam, Vera A. Morgan, Craig Morgan, Kim T. Mueser, Karoly Nikolich, Patricio O'Donnell, Michael O'Donovan, William A. Phillips, Wulf Rössler, Louis Sass, Akira Sawa, Jeremy K. Seamans, Steven M. Silverstein, William Spaulding, Sharmili Sritharan, Heike Tost, Peter Uhlhaas, Aristotle Voineskos, Michèle Wessa, Leanne M. Williams, Ashley Wilson, Til Wykes

    • Hardcover $19.75 £15.99
  • Dynamic Coordination in the Brain

    Dynamic Coordination in the Brain

    From Neurons to Mind

    Christoph von der Malsburg, William A. Phillips, and Wolf Singer

    An examination of how widely distributed and specialized activities of the brain are flexibly and effectively coordinated.

    A fundamental shift is occurring in neuroscience and related disciplines. In the past, researchers focused on functional specialization of the brain, discovering complex processing strategies based on convergence and divergence in slowly adapting anatomical architectures. Yet for the brain to cope with ever-changing and unpredictable circumstances, it needs strategies with richer interactive short-term dynamics. Recent research has revealed ways in which the brain effectively coordinates widely distributed and specialized activities to meet the needs of the moment. This book explores these findings, examining the functions, mechanisms, and manifestations of distributed dynamical coordination in the brain and mind across different species and levels of organization. The book identifies three basic functions of dynamic coordination: contextual disambiguation, dynamic grouping, and dynamic routing. It considers the role of dynamic coordination in temporally structured activity and explores these issues at different levels, from synaptic and local circuit mechanisms to macroscopic system dynamics, emphasizing their importance for cognition, behavior, and psychopathology.

    Contributors Evan Balaban, György Buzsáki, Nicola S. Clayton, Maurizio Corbetta, Robert Desimone, Kamran Diba, Shimon Edelman, Andreas K. Engel, Yves Fregnac, Pascal Fries, Karl Friston, Ann Graybiel, Sten Grillner, Uri Grodzinski, John-Dylan Haynes, Laurent Itti, Erich D. Jarvis, Jon H. Kaas, J.A. Scott Kelso, Peter König, Nancy J. Kopell, Ilona Kovács, Andreas Kreiter, Anders Lansner, Gilles Laurent, Jörg Lücke, Mikael Lundqvist, Angus MacDonald, Kevan Martin, Mayank Mehta, Lucia Melloni, Earl K. Miller, Bita Moghaddam, Hannah Monyer, Edvard I. Moser, May-Britt Moser, Danko Nikolic, William A. Phillips, Gordon Pipa, Constantin Rothkopf, Terrence J. Sejnowski, Steven M. Silverstein, Wolf Singer, Catherine Tallon-Baudry, Roger D. Traub, Jochen Triesch, Peter Uhlhaas, Christoph von der Malsburg, Thomas Weisswange, Miles Whittington, Matthew Wilson

    • Hardcover $19.75 £15.99