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Neuroscience research has exploded, with more than fifty thousand neuroscientists applying increasingly advanced methods. A mountain of new facts and mechanisms has emerged. And yet a principled framework to organize this knowledge has been missing. In this book, Peter Sterling and Simon Laughlin, two leading neuroscientists, strive to fill this gap, outlining a set of organizing principles to explain the whys of neural design that allow the brain to compute so efficiently.

A New Understanding of How Our Brain Became Remarkable

Humans are awesome. Our brains are gigantic, seven times larger than they should be for the size of our bodies. The human brain uses 25% of all the energy the body requires each day. And it became enormous in a very short amount of time in evolution, allowing us to leave our cousins, the great apes, behind. So the human brain is special, right? Wrong, according to Suzana Herculano-Houzel. Humans have developed cognitive abilities that outstrip those of all other animals, but not because we are evolutionary outliers.

Confessions of a Romantic Reductionist

What links conscious experience of pain, joy, color, and smell to bioelectrical activity in the brain? How can anything physical give rise to nonphysical, subjective, conscious states? Christof Koch has devoted much of his career to bridging the seemingly unbridgeable gap between the physics of the brain and phenomenal experience. This engaging book—part scientific overview, part memoir, part futurist speculation—describes Koch's search for an empirical explanation for consciousness.

Neuroscience, Embodiment, and the Future of Design

Although we spend more than ninety percent of our lives inside buildings, we understand very little about how the built environment affects our behavior, thoughts, emotions, and well-being. We are biological beings whose senses and neural systems have developed over millions of years; it stands to reason that research in the life sciences, particularly neuroscience, can offer compelling insights into the ways our buildings shape our interactions with the world. This expanded understanding can help architects design buildings that support both mind and body.

The cannabis plant has been used for recreational and medicinal purposes for more than 4,000 years, but the scientific investigation into its effects has only recently yielded useful results. In this book, Linda Parker offers a review of the scientific evidence on the effects of cannabinoids on brain and behavioral functioning, with an emphasis on potential therapeutic uses.

The vast differences between the brain’s neural circuitry and a computer’s silicon circuitry might suggest that they have nothing in common. In fact, as Dana Ballard argues in this book, computational tools are essential for understanding brain function. Ballard shows that the hierarchical organization of the brain has many parallels with the hierarchical organization of computing; as in silicon computing, the complexities of brain computation can be dramatically simplified when its computation is factored into different levels of abstraction.


Cellular Biophysics is a quantitatively oriented basic physiology text for senior undergraduate and graduate students in bioengineering, biophysics, physiology, and neuroscience programs. It will also serve as a major reference work for biophysicists.

New Perspectives on Mental Illness

Modern psychiatry is at a crossroads, as it attempts to balance neurological analysis with psychological assessment. Computational neuroscience offers a new lens through which to view such thorny issues as diagnosis, treatment, and integration with neurobiology. In this volume, psychiatrists and theoretical and computational neuroscientists consider the potential of computational approaches to psychiatric issues.

This textbook presents a wide range of subjects in neuroscience from a computational perspective. It offers a comprehensive, integrated introduction to core topics, using computational tools to trace a path from neurons and circuits to behavior and cognition. Moreover, the chapters show how computational neuroscience—methods for modeling the causal interactions underlying neural systems—complements empirical research in advancing the understanding of brain and behavior.

Retraining Subconscious Awareness

This is a book for readers who want to probe more deeply into mindfulness. It goes beyond the casual, once-in-awhile meditation in popular culture, grounding mindfulness in daily practice, Zen teachings, and recent research in neuroscience. In Living Zen Remindfully, James Austin, author of the groundbreaking Zen and the Brain, describes authentic Zen training—the commitment to a process of regular, ongoing daily life practice. This training process enables us to unlearn unfruitful habits, develop more wholesome ones, and lead a more genuinely creative life.

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