Emergent Brain Dynamics

From Strüngmann Forum Reports

Emergent Brain Dynamics

Prebirth to Adolescence

Edited by April A. Benasich and Urs Ribary

Experts explore the maturation of nonlinear brain dynamics from a developmental perspective and consider the relationship of neurodevelopmental disorders to early disruption in dynamic coordination.

Overview

Author(s)

Praise

Summary

Experts explore the maturation of nonlinear brain dynamics from a developmental perspective and consider the relationship of neurodevelopmental disorders to early disruption in dynamic coordination.

This volume in the Strüngmann Forum Reports series explores the complex mechanisms that accompany the dynamic processes by which the brain evolves and matures. Integrating perspectives from multiple disciplines, the book identifies knowledge gaps and proposes innovative ways forward for this emerging area of cross-disciplinary study. The contributors examine maturation of nonlinear brain dynamics across systems from a developmental perspective and relate these organizing networks to the establishment of normative cognition and pathology seen in many neurodevelopmental disorders.

The book looks at key mechanistic questions, including: What role does dynamic coordination play in the establishment and maintenance of brain networks and structural and functional connectivity? How are local and global functional networks assembled and transformed over normative development? To what degree do oscillatory patterns vary across development? What is the impact of critical periods, and which factors initiate and terminate such periods? It also explores the potential of new technologies and techniques to enhance understanding of normative development and to enable early identification and remediation of neurodevelopmental and neuropsychiatric disorders that may result from early disruption in dynamic coordination.

Contributors Sylvain Baillet, Yehezkel Ben-Ari, April A. Benasich, Olivier Bertrand, Gyorgy Buzsáki, Alain Chédotal, Sam M. Doesburg, Gordin Fishell, Adriana Galván, Jennifer N. Gelinas, Jay Giedd, Pierre Gressens, Ileana L. Hanganu-Opatz, Rowshanak Hashemiyoon, Takao K. Hensch, Suzana Herculano-Houzel, Mark Hübener, Mark, Matthias Kaschube, Michael S. Kobor, Bryan Kolb, Thorsten Kolling, Jean-Philippe Lachaux, Ulman Lindenberger, Heiko J. Luhmann, Hannah Monyer, Sarah R. Moore, Charles A. Nelson III, Tomáš Paus, Patrick L. Purdon, Pasko Rakic, Urs Ribary, Akira Sawa, Terrence J. Sejnowski, Wolf Singer, Cheryl L. Sisk, Nicholas C. Spitzer, Michael P. Stryker, Migranka Sur, Peter J. Uhlhaas

Hardcover

$50.00 X ISBN: 9780262038638 344 pp. | 9 in x 6 in 26 color illus., 4 b&w illus., 8 halftones

Editors

April A. Benasich

April A. Benasich is Elizabeth H. Solomon Professor of Developmental Cognitive Neuroscience and Director of the Infancy Studies Laboratory at the Center for Molecular and Behavioral Neuroscience at Rutgers University–Newark, where she is also Director of the Carter Center for Neurocognitive Research.

Urs Ribary

Urs Ribary is Endowed BC LEEF Leadership Chair in Cognitive Neuroscience, Director of the Behavioral and Cognitive Neuroscience Institute (BCNI), and Professor in Psychology, Pediatrics, and Psychiatry at Simon Fraser University and the University of British Columbia in Vancouver.

Endorsements

  • This volume of edited chapters by many leaders in this important field of study, is the product of one of the remarkable meetings organized by the Ernst Strungmann Forum, based on an in-depth symposium examining and debating the details of the fundamentally important question, 'how do early experiences influence brain development to determine who we become?' Much important information is provided by this influential volume, and essential unresolved questions, problems, and concerns are elucidated, making this an important read for experts and for those newly introduced to the issues raised therein.

    Fred H. Gage

    Adler Professor, Laboratory of Genetics, Salk Institute for Biological Studies

  • This highly readable volume gathers together an impressive group of neuroscientists who explore and debate how early neural plasticity and critical periods allow the developing brain's functional organization to emerge and shape our complex cognitive function as we mature. Babies grow and learn at a phenomenal rate. During those early formative years, the brain experiences tremendous changes in size, shape, and connectivity among its trillions of synapses. Many of these changes continue on well into adulthood. Despite these incomprehensibly complex dynamics, we maintain a relatively stable sense of cognition and self as we grow older. This volume captures what we currently know about early brain dynamics and deftly tackles fundamental, and still unanswered, questions including how our brains balance the ongoing dynamic, plastic underpinnings of our neurobiology with the relative stability of our cognition.

    Bradley Voytek

    Professor of Neuroscience, UC San Diego, and author of Do Zombies Dream of Undead Sheep?

  • This book offers the reader a thorough sampling of experimental approaches to understanding how neuronal assemblies are formed and maintained in the brain, and how they face the challenge of growth and development through adolescence and beyond—a must read for anyone interested in the wet stuff supporting the mind.

    Albert Galaburda

    Professor of Neurology and Neuroscience, Harvard Medical School, and Co-director, Mind Brain Behavior Interfaculty Initiative, Harvard University

  • This new volume in the Ernst Strüngmann Forum series uses a truly interdisciplinary approach to tackle the complex but core issue of emergent synchronization in brain activity. Unlike a typical collection of stand-alone chapters, the volume captures the exchange of an impressive group of scientists engaged in vigorous discussion and debate, merging well-accepted and cutting-edge findings into a revolutionary framework that could explain how functional synchronization in the healthy adult brain comes to be. Anyone interested in the brain—including neuroscientists who do not focus on brain development—will benefit from reading it. Indeed, this book may trigger a paradigm shift in our understanding of the role of brain dynamics subserving healthy function and disease, capturing the extraordinary progress that has been made to date, highlighting just how much is still unknown, and providing a blueprint for future research in this emerging field.

    Holly Fitch

    Professor of Behavioral Neuroscience and Director, Murine Behavioral Phenotyping Facility, Department of Psychological Sciences, University of Connecticut