**Hardcover**| Out of Print | ISBN: 9780262041997 | 480 pp. | 8 x 10 in | 165 illus. | October 2001

**Paperback**|

**$55.00 Short**|

**£40.95**| ISBN: 9780262541855 | 480 pp. | 8 x 10 in | 165 illus. | August 2005

## Essential Info

## Instructor Resources

## Theoretical Neuroscience

## Overview

Theoretical neuroscience provides a quantitative basis for describing what nervous systems do, determining how they function, and uncovering the general principles by which they operate. This text introduces the basic mathematical and computational methods of theoretical neuroscience and presents applications in a variety of areas including vision, sensory-motor integration, development, learning, and memory.

The book is divided into three parts. Part I discusses the relationship between sensory stimuli and neural responses, focusing on the representation of information by the spiking activity of neurons. Part II discusses the modeling of neurons and neural circuits on the basis of cellular and synaptic biophysics. Part III analyzes the role of plasticity in development and learning. An appendix covers the mathematical methods used, and exercises are available on the book's Web site.

## About the Author

Larry Abbott is Professor of Neuroscience and Co-Director of the Center for Theoretical Neuroscience at Columbia University.

## Reviews

**M. Brandon Westover**,

*Philosophical Psychology*

**Dmitri Chklovskii**,

*Neuron*

## Endorsements

—

**Phillip S. Ulinski**

—

**P. Read Montague**, Professor, Division of Neuroscience, and Director, Center for Theoretical Neuroscience, Baylor College of Medicine

—

**Bard Ermentrout**, Department of Mathematics, University of Pittsburgh

*Theoretical Neuroscience*provides a rigorous introduction to how neurons code, compute, and adapt. It is a remarkable synthesis of advances from many areas of neuroscience into a coherent computational framework. This book sets the standards for a new generation of modelers.”

—

**Terrence J. Sejnowski**, Howard Hughes Medical Institute, Salk Institute for Biological Studies, and University of California, San Diego

—

**Christof Koch**, Lois and Victor Troendle Professor of Cognitive and Behavioral Biology, California Institute of Technology

*Theoretical Neuroscience*marks a milestone in the scientific maturation of integrative neuroscience. In the last decade, computational and mathematical modelling have developed into an integral part of the field, and now we finally have a textbook that reflects the changes in the way our science is being done. It will be a standard source of knowledge for the coming generation of students, both theoretical and experimental. I urge anyone who wants to be part of the development of this science in the next decades to get this book. Read it, and let your students read it.”

—

**John Hertz**, Nordita (Nordic Institute for Theoretical Physics), Denmark